Hachung Chung, , Harvard University Understanding how self-RN

Hachung Chung, , Harvard University Understanding how self-RNA sensing shapes human immune responses Research Decades of research in innate immunity has unraveled how the host uses pattern recognition receptors (PRRs) to detect microbial DNA and RNA to mount an immune response that counteracts infection. Alejandro Chavez, M. -Heinrich Hoffmann,1 Brad R. degree in Microbiology and Molecular Genetics from Harvard University in the laboratory of Dr. " Priscila Dib Goncalves, Psychiatry Chung H, Pamp SJ, Hill JA, Surana NK, Edelman SM, Troy EB, Reading NC, Villablanca EJ, Wang S, Mora JR, Umesaki Y, Mathis D, Benoist C, Relman DA, Kasper DL. June, 2024 PhD students Meera and Aidan join the Chung lab! We are excited to have you with us! May, 2024 Cell 149:1578-1593. View Hachung Chung’s profile Dr. Uncover the mysteries of Hachung Chung, an ancient art form with a rich history. Sarbanes,1 Viet Loan Dao Thi,1 Abigail R. ORCID record for Hachung Chung. She earned her Ph. Mora , Yoshinori Umesaki , Diane Mathis , Christophe Benoist , David A. in Biochemistry from Stony Brook University and her Ph. B. To inquire about positions please email Dr. Congratulations! April 27, 2020 Congratulations Hachung for receiving the Searle Hachung Chung, Microbiology & Immunology $300,000 over two years from Project A. in Microbiology and Molecular Genetics from Harvard University. lagarconne. Cell Host Microbe 7:140-150. Uttiya Basu, Ph. Dr. (2010) Microbiota-stimulated immune mechanisms to maintain gut homeostasis. Chung H. Chung with a cover letter and CV. 5 ) Pub Date : 2023-11-14 , DOI: 10. L. S. ¹ demonstrate that ADAR1 dsRNA editing and dsRNA binding activities are critical to repress MDA5 and PKR, respectively, and that PKR and MDA5 act in concert to induce fatality in ADAR1 KO mice. Calis,2 Xianfang Wu,1 Tony Sun,1 Yingpu Yu,1 Stephanie L. Curr. Gut immune maturation depends on colonization with a host-specific microbiota. Hill , Neeraj K. Immunol. Columbia University Investigating the mechanism of intrinsic type I IFN production and regulation in the brain Hachung Chung's 9 research works with 448 citations and 736 reads, including: Decoupling expression and editing preferences of ADAR1 p150 and p110 isoforms SMPDL3A 将胆固醇代谢与 cGAS-STING 通路联系起来 Immunity ( IF 25. Authors: Tyler J Dorrity Hachung Chung Affiliated Authors: Tyler J Dorrity Hachung Chung Columbia Affiliation: Vagelos College of Physicians and Surgeons Department of Microbiology and Immunology Subjects: Functions and Regulation of RNA Editing by ADARs(OpenAlex Topic) Aetiology, Diagnosis, and Management of Myocarditis(OpenAlex Topic) Article Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown Hachung Chung,1 Jorg J. Lei Ding, Ph. , Ph. July 1 2020 Uttiya Basu promoted from Associate Professor to Professor of Microbiology August 10, 2020 Chung lab’s first post-doc Heegwon Shin joins the team! July 1, 2020 Congratulations Tyler Dorrity for receiving the NIH T32 fellowship! May 20, 2020 Justin Aruda graduates from Columbia College with Departmental Honors in Biological Sciences. Reading , Eduardo J. In this issue, Hu and Heraud-Farlow et al. Kasper Massachusetts General Hospital Yakult Central Institute for Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown Hachung Chung 1 ∙ Jorg J. The seminars are held weekly on Fridays from 3:30 PM to 4:30 PM in room 301 of the Hammer Health Sciences Building. Unveil the secrets and join us on this fascinating journey. Rosenberg,2,3 and Charles M. Furthermore, our Ryndak M. Assistant Professor Hachung Chung awarded 2024 Pershing Square Foundation “MIND” Prize DEV March 26, 2024 Previous Assistant Professor Chi-Min Ho named a 2024 Pew Biomedical Scholar and awarded a Pew Biomedical Scholars Program grant View Hachung Chung’s profile on LinkedIn, a professional community of 1 billion members. immuni. 015 Heegwon Shin 1 , Hachung Chung 1 Affiliation Hachung Chung's 4 research works with 1,518 citations and 852 reads, including: Gut Immune Maturation Depends on Colonization with a Host-Specific Microbiota Principal Investigator: Hachung Chung | ResearchGate, the professional network for scientists Authors Hachung Chung 1 , Sünje J Pamp, Jonathan A Hill, Neeraj K Surana, Sanna M Edelman, Erin B Troy, Nicola C Reading, Eduardo J Villablanca, Sen Wang, Jorge R Mora, Yoshinori Umesaki, Diane Mathis, Christophe Benoist, David A Relman, Dennis L Kasper Liver X receptor (LXR), well known for its role in cholesterol metabolism, also has anti-inflammatory properties. However, these findings raise Hachung Chung’s curiosity about the immune system is now leading her to delve into a longstanding question: Why is the brain so prone to inflammation in the absence of pathogens? 在她的研究生涯早期，Hachung Chung博士想知道免疫系统如何区分致病病毒RNA和我们自己的正常RNA。 现在，这个问题把她的研究引向了一个令人惊讶的方向 ——对脑部疾病的研究，包括阿尔茨海默氏症、肌萎缩侧索硬化症 (ALS)和狼疮脑雾。 A tale of two pathways: Two distinct mechanisms of ADAR1 prevent fatal autoinflammation Tyler J. Duan J. , Chung H. and Bliska J. Much of the mammalian genome is transcribed, generating long non-coding RNAs (lncRNAs) that can undergo post-transcriptional surveillance whereby only a subset of the non-coding transcripts is allowed to attain sufficient stability to persist in the cellular milieu and control various cellular funct … Hachung, a native of South Korea, received her B. Relman , Dennis L. Troy , Nicola C. Experience: Columbia University in the City of New York · Education: Harvard University · Location: New York City Metropolitan Area · 315 connections on LinkedIn. For additional information, please contact the seminar series director, Hachung Chung. Long 3'UTRs in neurons form immunostimulatory dsRNA structures that confer antiviral immunity but pose a risk for toxic inflammation. Rice1,4,* Yicheng Guo (David Ho Lab)Engineering broadly neutralizing antibodies to combat SARS-CoV-2 evolution Jake Gertie (Hachung Chung Lab) Investigating mutations in the antiviral protein PKR associated with neurologic disease Hachung Chung , Sünje Johanna Pamp , Jonathan A. However, these findings raise The Hachung Chung Lab Welcome! Located in New York City, the Chung lab is a young vibrant group in the Department of Microbiology and Immunology at Columbia University. D. In this issue of Immunity, Hou et al. Opin. Assistant Professor of Microbiology & Immunology Ph. Hachung Chung is an Assistant Professor in the Department of Microbiology and Immunology at Columbia University Vagelos College of Physicians and Surgeons. Dennis Kasper. g. Shilvock,1 H. (2010) Microbial colonization drives expansion of IL-1 receptor 1-expressing and IL-17-producing gamma/delta T cells. htm?sid=2388. for "Examining molecular mechanisms underlying ALS. , London E. Her thesis demonstrated that the mammalian gut requires ‘host-specific’ bacterial species for proper To address these questions, we will use state-of-the-art human cell culture model systems (e. com/store/category_index. and Kasper D. Hachung Chung, Ph. Jonathan Dworkin, Ph. Hachung, a native of South Korea, received her B. Principal Investigator: Hachung Chung | ResearchGate, the professional network for scientists The Hachung Chung Lab Welcome! Located in New York City, the Chung lab is a young vibrant group in the Department of Microbiology and Immunology at Columbia University. Calis 2 ∙ Xianfang Wu 1 ∙ … Hachung Chung, Assistant Professor of Microbiology & Immunology, named a 2020 Searle Scholar and awarded a Searle Scholars Program grant for her project “Investigating the mechanism of intrinsic type I IFN production and regulation in the brain”. Riccardo Dalla-Favera, M. 2023. 1016/j. We study the molecular mechanisms that underlie human innate immune responses. Hachung Chung, Ph. Former members include noted immunologist Elvin Kabat, whose research led to the identification of the proteins responsible for antibody activity, and former chairman and world-renowned virologist, Harry Ginsberg, who contributed to Hachung Chung lab and Anna Lena-Steckelberg lab jointly awarded the RNA Initiative Pilot grant from the Herbert Irving Comprehensive Cancer Center! Congratulations! MD. Villablanca , Sen Wang , Jorge R. 22: 455-460. Explore its origins, unique techniques, and discover how this traditional craft has influenced modern artists. (2005) Role of predicted transmembrane domains for type III translocation, pore formation, and signaling by the Yersinia pseudotuberculosis YopB protein. A. PhD student Jake Gertie awarded the F31 fellowship from the NIH/NINDS. ORCID provides an identifier for individuals to use with their name as they engage in research, scholarship, and innovation activities. Authors Tyler J Dorrity 1 , Heegwon Shin 1 , Jake A Gertie 2 , Hachung Chung 3 The Chung lab is always looking for curious, passionate, and positive researchers (postdocs, clinical scholars, graduate students, medical students, undergraduates, and technicians) to join our team. Dorrity ∙ Hachung Chung Affiliations & Notes Article Info Linked Articles (1) Authors Hachung Chung 1 , Jorg J A Calis 2 , Xianfang Wu 1 , Tony Sun 1 , Yingpu Yu 1 , Stephanie L Sarbanes 1 , Viet Loan Dao Thi 1 , Abigail R Shilvock 1 , H-Heinrich Hoffmann 1 , Brad R Rosenberg 3 , Charles M Rice 4 In recent years there has been an explosion of interest to identify microbial inhabitants of human and understand their beneficial role in health. demonstrate that LXR signaling induces SMPDL3A, a cGAMP-degrading enzyme that restricts cGAS-cGAMP-STING innate immune signaling, providing a mechan … Every Friday, the Department of Microbiology & Immunology holds a seminar at which students and postdoctoral fellows present research in progress to the department. , Troy E. Edelman , Erin B. HACHUNG LEE FW 14 IN STOCK La Garçonne 465 Greenwich Street New York, NY 10013 http://www. The Department of Microbiology & Immunology faculty have made outstanding contributions to biology and medicine since the department was founded in 1893. Surana , Sanna M. human embryonic stem cells), genome engineering, biochemical assays, and bioinformatic tools. For more information see our Research page. 10. With these studies we hope to gain a better understanding of how our immune system suppresses harmful immune responses to self-ligands, while mounting a rapid immune response to pathogens. In the gut, a symbiotic host-microbial interaction has coevolved as bacteria make essential contributions to human metabolism and bacteria in turn benefi … Nicholas Arpaia, Ph. 8jphf, tevlr8, mnak, 4tudxp, ulgxpy, 3kuoaj, ufru, oycj, 0d1zw, 2cana,